Shortly after losing starting safety Talanoa Hufanga for the year to a torn ACL, the 49ers were worried that they would be down another body in the secondary after George Odum suffered a biceps injury that the team feared could be season-ending. Luckily, they were wrong. San Francisco activated Odum off of injured reserve today, opening a roster spot for him by placing defensive end Clelin Ferrell on IR in his place. 
Odum, a former undrafted free agent, signed a three-year contract with the 49ers after a breakout year that saw him start seven games for the Colts. Up until that breakout season, Odum had seen most of his use coming on special teams. The patient defender was given his opportunity to start thanks to multiple injuries to starters Khari Willis and Andrew Sendejo. He took advantage of that opportunity, finishing sixth on the team with 55 total tackles while recording an interception and two passes defensed. While Odum may not be a game changer on the 49ers defense, the depth he provides at safety will be a welcome one as San Francisco starts their 2023 playoffs.
Ferrell, a former top-four pick out of Clemson, has ultimately failed to live up to his draft stock over his five years in the league. After seeing his fifth-year option declined by the Raiders, Ferrell signed a one-year deal to come to San Francisco. Despite not meeting expectations in Las Vegas, Ferrell stepped in as a full-time starter for the 49ers this season. Ferrell hasn’t been very productive as a pass rusher (only 3.5 sacks), but he hasn’t needed to be as Nick Bosa (10.5), Javon Hargrave (7.0), and Arik Armstead (5.0) have fed off of their combined pass rushing effort. With Ferrell out with a knee injury, trade acquisition Chase Young, who has been coming off the bench since being acquired before Week 10, will once again step into a starting role.
In addition to the two IR transactions, the team also announced their standard gameday practice squad elevations for the Divisional Round of the playoffs. Defensive tackles Alex Barrett and T.Y. McGill will be called up to add some depth to the defensive line against the Packers tonight.