The Lions have placed cornerback Ifeatu Melifonwu on the injured reserve list (Twitter link via NFL.com’s Ian Rapoport). To take his place, they’ve promoted fellow corner Daryl Worley from the practice squad to the active roster. 
Melifonwu will need at least a few weeks to recover from the thigh injury he suffered on Monday night. Lions head coach Dan Campbell isn’t exactly sure when he’ll return, but he did tell reporters that the rookie will be out for a “significant amount of time.” It’s a bad blow for Detroit — the third-rounder out of Syracuse was enjoying a strong start to his pro career. He notched a fumble recovery in his Week 1 debut and earned a start in Week 2 against the Packers.
Of course, the Lions were already without Jeff Okudah, who has been ruled out for the season. Amani Oruwariye will remain the starter at one of the cornerback spots, likely with help from former undrafted safety Bobby Price.
Worley should factor into the banged-up secondary as well, especially since he has 54 career starts to his credit. Still only 26, Worley’s resume includes five interceptions and 37 passes defensed.