Anthony Castonzo Experiences Setback

A hamstring injury has bothered Anthony Castonzo for months now, but after missing Week 1, the Colts’ starting left tackle was on track to suit up Sunday. He won’t, however.

Frank Reich confirmed Castonzo experienced a setback during Wednesday’s practice and is out Sunday, per Mike Chappell of IndySportsCentral.com (on Twitter).

The first-year coach added the Colts are not yet considering IR as an option for Castonzo, (Twitter link via Chappell), but the eighth-year blocker’s been battling this issue since before training camp began. Castonzo returned from an offseason hamstring injury in camp, but a setback in August caused him to miss most of Indianapolis’ camp schedule.

Castonzo’s started every game he’s played as a Colt, 105 dating back to the first-rounder’s 2011 debut. He’s played a full 16 games in five of his seven seasons and has never missed more than four in a season. The Colts started rookie Braden Smith in Castonzo’s place last week.

The Colts, though, will deploy a new O-line combination given that J’Marcus Webb is now on IR.

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