NOV. 10: Brissett is considered week-to-week, as Ian Rapoport of NFL.com tweets. The Colts hope Brissett will return for next week’s game against the Jaguars, but nothing is certain at this point.

NOV. 9: Jacoby Brissett has been downgraded to ‘OUT’ for the Colts matchup against the Dolphins tomorrow, reports Stephen Holder of The Athletic (via Twitter). This means Brian Hoyer will take over as the starting quarterback.

Meanwhile, the Colts made a handful of moves to accommodate this lineup change. The team announced that quarterback Chad Kelly (along with wideout Marcus Johnson) has been promoted from the practice squad. To make room on the roster, the team has waived wideout Deon Cain and defensive tackle Kyle Peko.

Brissett injured his MCL during last week’s loss to the Steelers, putting a sudden halt on his breakout campaign. Taking over for Andrew Luck, the 26-year-old has completed 64.8-percent of his passes for 1,649 yards, 14 touchdowns, and three picks. He’s also added another 37 rushes for 110 yards and one score. Hoyer filled in admirably during last week’s loss, throwing for 168 yards and three touchdowns. He’ll be getting his first start since 2017.

Kelly, the Mr. Irrelevant of the 2017 Draft, was suspended for the first two games of this season. After getting waived by the Colts, he subsequently joined the team’s practice squad. Should Hoyer be sent to the sideline, Kelly could see himself playing in his second career game. Johnson, a former undrafted free agent out of Texas, has 11 career receptions for 147 yards and one touchdown.

Cain, a 2018 sixth-round pick, spent his rookie year on the injured reserve as he recovered from an ACL injury. The 23-year-old got into seven games (three starts) this season, hauling in four receptions for 52 yards. Peko, 26, was claimed off waivers from the Bills earlier this week.