With more teams debuting their preseasons Friday night, here’s the latest out of the NFC, beginning with one of the teams that indeed begins its 2018 run tonight.

• A fourth-round pick two years ago, Miles Killebrew may be moving to a different position in order to increase his chances of making the Lions‘ 53-man roster. The third-year safety’s been working exclusively as a linebacker in practice as of late, Dave Birkett of the Detroit Free Press notes. Killebrew started three games at safety for the Lions last season, but Birkett adds that the Southern Utah product was working as the fifth safety during camp in a unit that’s now including former full-time cornerback Quandre Diggs. Rookie Tracy Walker was also running ahead of Killebrew.
• Nick Easton‘s season-ending injury now has the Vikings down three starters, with Pat Elflein still on the PUP list and Mike Remmers also sidelined. Tom Compton is the favorite to fill in for Easton at left guard, and ESPN.com’s Courtney Cronin notes the Vikings were eyeing the former Redskins and Bears blocker in the past prior to signing him this offseason. Compton, though, has only made 16 starts in six seasons. The Vikings are likely to keep Compton at guard rather than have him also work at tackle, Mike Zimmer said. Second-year man Danny Isidora looks to the the top insurance option at the other guard spot in case Remmers, down with an ankle injury presently, doesn’t return soon, per Cronin. A fourth-year UDFA out of Portland State, Cornelius Edison is currently working as Minnesota’s first-team center in Elflein’s absence.
• The Buccaneers will be without Vernon Hargreaves for a bit, potentially the rest of the preseason, with a groin injury. Dirk Koetter, however, doesn’t expect the former first-round pick to miss any regular-season time because of this malady (Twitter link, via the Tampa Bay Times’ Rick Stroud).
• The 49ers will be dealing with similar timelines involving key personnel. Likely tight end starter George Kittle and No. 2 running back Matt Breida suffered separated shoulders in San Francisco’s preseason opener Thursday night, per Eric Branch of the San Francisco Chronicle. Both will miss the remainder of the preseason calendar. Kyle Shanahan said the earliest either will return is Week 1.
• Derrius Guice‘s ACL tear deprives the Redskins of a potential impact player being part of their 2018 offense, and they will likely turn to former starter Rob Kelley in his place, Rich Tandler of NBC Sports Washington writes. He expects Samaje Perine, who was in danger of not making the roster prior to Guice’s injury, to work in off the bench on early downs. Tandler adds the Redskins could go after a veteran back, and while many are available, it’s not certain the team will move in that direction just yet. Kelley rushed for 704 yards (4.2 per carry) in 2016, a season that featured him start down the stretch, but gained just 194 last year (3.1 per tote) in seven games as Washington’s starter.